![]() Hyposalivation prior to and during treatment is associated with an increased risk of oral mucositis. This is to some extent related to the treatment regimens. Generally, patients with hematologic malignancies have an increased rate of oral mucositis compared with those with solid tumors. Chronic irritation from ill-fitting prostheses or faulty restorations can predispose patients to the development of oral mucositis due to local irritation and trauma. Diseases such as kidney disease, diabetes or HIV/AIDS. Gender (females appear to be more likely than males to develop mucositis) Smoking or chewing tobacco and drinking alcohol. When caused by chemotherapy, mucositis is usually due to the low white blood cell count when caused by radiation, mucositis is usually due to the necrotic and inflammatory effect of radiation energy on oral mucosa.įactors that can increase the likelihood of developing mucositis, or that can make it worse if it does occur, include: The majority of oral cancer patients receiving chemotherapy in combination with radiation will experience at least some degree of mucositis. The combination of mucus, excess saliva and pain can make it difficult or even impossible to eat. In a worst case, the mucous membrane of the patient’s entire mouth and tongue can be coated by a white mucus coating that is up to a millimeter thick. Increased mucus or thicker saliva in the mouthĪn extreme case of the condition is called confluent mucositis. Soft, whitish patches or pus in the mouth or on the tongue Feeling of dryness, mild burning, or pain when eating food Sores in the mouth or on the gums or tongue ![]() It has a significant effect on the patient’s quality of life and can be dose-limiting (i.e., requiring a reduction in subsequent chemotherapy doses). It can lead to several problems, including pain, nutritional problems as a result of inability to eat, and increased risk of infection due to open sores in the mucosa. Oral mucositis is probably the most common, debilitating complication of cancer treatments, particularly chemotherapy and radiation. The oral cavity is the most common location for mucositis. The part of this lining that covers the mouth, called the oral mucosa, is one of the most sensitive parts of the body and is particularly vulnerable to chemotherapy and radiation. Mucosal tissue, also known as mucosa or the mucous membrane, lines all body passages that communicate with the air, such as the respiratory and alimentary tracts, and have cells and associated glands that secrete mucus. This entry was posted on Septemby woodlandhills pharmacy.Mucositis occurs when cancer treatments break down the rapidly divided epithelial cells lining the gastro-intestinal tract (which goes from the mouth to the anus), leaving the mucosal tissue open to ulceration and infection. Magic Mouthwash formulation on the National Cancer Insitute drug directory.After using the mouthwash, drinking and eating should be avoided for about a half an hour so that the medicine will stay on the affected areas. Directions may vary depending on the formulation and what it is being used to treat. This should be done around every four hours. The most commonly prescribed directions for magic mouthwash are to swish for two minutes then spit and swallow. Maalox/Mylanta – helps the active ingredients stay on the sores and affected areas of the mouth and throat longer.Tetracycline – antibiotic for treating infection.Hydrocortisone – steroid that treats inflammation.Lidocaine – an anesthetic frequently used in topical formulations that can reduce pain by numbing the mouth and throat.Nystatin – antifungal for treating candidiasis.Diphenhydramine is marketed commercially as Benadryl. Diphenhydramine – an antihistamine that can reduce inflammation and pain.Common ingredients used in magic mouthwash formulations include: Each mouthwash usually contains an antibiotic, an antihistamine, an antifungal, a corticosteroid, and an antacid. ![]() Each of these mouthwashes includes different ingredients and strengths although there is a consistency in the types of drugs used. There are multiple formulations that are called “Magic Mouthwash” used to treat mouth sores and sore throat.
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